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As established earlier, the menopausal transition is associated with a shift toward chronic low-grade inflammation, driven partly by the loss of estrogen's anti-inflammatory signaling and partly by the accumulation of metabolically active visceral fat

Hyperglycemia or hypoglycemia with changes in insulin regimen: Make changes to a patients insulin regimen (e.g., insulin strength, manufacturer, type, injection site or method of administration) under close medical supervision with increased frequency of blood glucose monitoring (5.2)

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Available from: Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity (SELECT)

Volz A, Gke R, Lankat-Buttgereit B, Fehmann HC, Bode HP, Gke B

Ann N Y Acad Sci (2000) 921:4737