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Research shows that training volume can be reduced by up to 66% without muscle loss as long as intensity remains high

This is why youre hearing we dont know so oftenbecause genuinely, we dont have complete information yet

Genetics and Epigenetics : Genetic predisposition and early life exposures can affect how fat is stored

Epigenetic alterations associated to HS include chromatin remodeling and aberrant DNA methylation of cytokine genes (like IL-17F and CXCL10), that can result in a persistent and self-amplifying pro-inflammatory state even in the absence of a primary genetic variants [62, 63]

10.1038/ncpendmet0787 [DOI] [PubMed] [Google Scholar] Dybciak P., Raczkiewicz D., Humeniuk E., Powrzek T., Gujski M., Maecka-Massalska T., et al

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