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Crees PCOS research has shown that the condition is associated with obesity and metabolic associated steatotic liver disease (MASLD) which can lead to Type 2 diabetes

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Furthermore, there remains great uncertainty related to how and where PPAR agonists act to regulate energy and glucose metabolism 51

Abbreviations: RCT: randomized clinical trial, BBR: berberine, RIAIS: Radiation-induced acute intestinal symptoms, RILI:radiation-induced lung injury

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