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Furthermore, GLP-1R expression in the hippocampus is higher in AUD patients compared to controls (Farokhnia et al., 2022)

[DOI] [Google Scholar] 81.Siamashvili M., Davis S.N

A meta-analysis of 55 randomized controlled trials (comprising 33,350 participants) showed no statistically significant increase in the risk of pancreatitis with GLP-1 agonists compared with controls (OR: 1.05, 95% CI: 0.37-2.94)

5.2 Acute Pancreatitis Acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, has been observed in patients treated with GLP-1 receptor agonists, including RYBELSUS [see Adverse Reactions (6)]
