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Knowing how GLP-1 works in your body helps doctors give the best care and make you feel better

Self controlled case series methods: an alternative to standard epidemiological study designs

In people with obesity or metabolic dysfunction, this signaling system is often impaired meaning the fullness and satiety signals don't fire the way they should
Accordingly, in vitro and ex vivo studies have shown that exposure to saxagliptin (135, 136) but not sitagliptin (136), results in altered cardiac electrophysiology and is associated with impaired cardiomyocyte contractility

Obesity and diabetes are risk factors for post-surgery complications because they increase inflammation and disturb blood clotting and heart function
