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Starting body mass index in the extension phase averaged about 37 kg/m2 (well into the obese range)

The most striking protective effects of SGLT2is were a marked reduction in hospitalization for heart failure and a remarkable reduced progression of chronic kidney disease

[DOI] [PMC free article] [PubMed] 37.Kim YC, Park JH, Prausnitz MR

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one found an overall relative risk of 1.31, and the second an odds ratio of 1.23