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Apitegromab (SRK-015), an investigational new drug developed by Scholar Rock, is a fully human IgG4 monoclonal antibody that specifically binds to human Pro-GDF8 or latent GDF8 without binding to mature GDF8 or other closely related growth factors

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The present study was designed to assess GLP-1-induced diuresis and natriuresis in rats with HF and its interactions with renal nerve activity

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doi: 10.1038/s41392-022-01149-x

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