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Potential drug interactions for metformin and Ozempic Anytime you take more than one drug, consider how all your medications may interact
Consistent with this, GLP-1, exendin-4, and the DPP-4 inhibitor sitagliptin reduced proximal tubular sodium reabsorption in rats [660,761,769,770] and humans [663]
NICE guidance emphasises the importance of individualised treatment approaches and regular monitoring to optimise both efficacy and tolerability of GLP-1 therapies

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