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While this review centers on SMAD-dependent pathways, SMAD-independent signaling also contributes to obesity-related metabolic disorders (Fig

The onset of cardiovascular disease (CVD) is proposed to be mediated by a multitude of drivers, like metabolic stressors, cardiac and vascular dysfunction, impaired angiogenesis, and the development of atherosclerosis [2]

T1DM is defined as an autoimmune disease, resulting in insulin deficiency

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Molecular Metabolism,2019, 30