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Patients who remain at lower doses (2.55 mg) due to side effect concerns may not achieve optimal therapeutic benefit
In rats, infusion of GRP stimulates the secretion of GLP-1 while administration of the GRP antagonist BW10 blocks GLP-1 secretion when fat is directly administered into the duodenum [339]
It is important to consume the RDA for protein (0.8 grams / kilogram of body weight) to ensure muscle mass is maintained during active weight loss
Proven cardiovascular safety from SELECT (20% MACE reductio
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