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Description
In 2024, the FDA approved Zepbound as the first GLP-1 medication specifically indicated to treat obstructive sleep apnea (OSA) in adults with obesity
Lenharo, M
[DOI] [PubMed] [Google Scholar] 55.Moore B
The decreased GLP-1 secretions could be due to receptor internalization
However, emerging data and mechanistic plausibility suggest that certain populations may be at higher risk of suboptimal intake or depletion, particularly with prolonged therapy, rapid weight loss, restricted dietary variety or pre-existing marginal nutrient status
Fatigue during the first one to two weeks is common as the body adjusts to significantly lower caloric intake
