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Their method was much less cumbersome than the one used back in 1968 by Erich Wnsch and his coworkers in Munich, Germany, to provide the first total synthesis of the molecule

Inorganic nanoparticles: toxic effects, mechanisms of cytotoxicity and phytochemical interactions
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Methods: Thirty patients with either diarrhea or mixed type IBS were recruited and undertook low FODMAP diet for 12 weeks
