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95% CI, 0.68-0.80), neovascular glaucoma (HR, 0.78

Chronic high-fat feeding increases GIP and GLP-1 secretion without altering body weight

Tirzepatide is FDA-approved for type 2 diabetes management and for chronic weight management, also under established brand names

Cardiovascular exercise also helps, primarily through direct calorie expenditure and improvements in insulin sensitivity, but it is less effective than resistance training at preserving the muscle mass whose loss contributes to stalls

Today, a new generation of GLP-1 receptor agonists has transformed obesity and metabolic disease research and treatment

doi:10.1016/j.diabres.2016.10.024 147