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By analogy with semaglutide (where the STEP-4 withdrawal trial demonstrated substantial weight regain within 12 months of discontinuation), researchers should anticipate that weight regain is likely following cessation of any GLP-1 class compound, including retatrutide

By week 12, most people have lost 812% of body weight

In comparisons between tirzepatide and semaglutide, when HbA 1c was measured in mmol/mol, all tirzepatide doses were comparable with semaglutide 2.0 mg and superior to semaglutide 1.0 mg and 0.5 mg (ESM Table 6)

If you engage in physical activity after taking your injection, its unlikely to cause a rapid drop in blood sugar levels

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