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By analogy with semaglutide (where the STEP-4 withdrawal trial demonstrated substantial weight regain within 12 months of discontinuation), researchers should anticipate that weight regain is likely following cessation of any GLP-1 class compound, including retatrutide

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By week 12, most people have lost 812% of body weight

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In comparisons between tirzepatide and semaglutide, when HbA 1c was measured in mmol/mol, all tirzepatide doses were comparable with semaglutide 2.0 mg and superior to semaglutide 1.0 mg and 0.5 mg (ESM Table 6)

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If you engage in physical activity after taking your injection, its unlikely to cause a rapid drop in blood sugar levels

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