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The approved regimen begins at 2.5 mg weekly for four weeks, then increases to 5 mg weekly for four weeks, with further escalations to 7.5 mg, 10 mg, 12.5 mg, and a maximum of 15 mg weekly, each maintained for at least four weeks

You can read more about the side effects of each drug here: Does Ozempic work better than metformin

All treatments significantly elevated the serum levels of kynurenine, but they failed to affect the kynurenine-Trp ratio
Not a ton of controversy there, either

This presented an enormous obstacle for creating GLP-1 medications

Psychiatrists 68 (1), e20
