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71 Besides, some SGLTs in CNS have been shown to act as glucose sensors, by counter-regulating hypoglycemia

Day JW, Ottaway N, Patterson JT et al (2009) A new glucagon and GLP-1 co-agonist eliminates obesity in rodents

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[5] While these medications offer significant therapeutic advantages, they can influence blood pressure through multiple mechanisms, including weight loss and potentially natriuresis (increased sodium excretion), typically producing modest reductions of 2-6 mmHg in systolic blood pressure

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Iwasaki H, Kajimura M, Osawa S, Kanaoka S, Furuta T, Ikuma M, et al