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One drawback for further development of both quinoxaline- and pyrimidine-based leads is the chemical instability in the presence of nucleophiles (Sloop et al., 2010)
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Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss
Retatrutideis a novel synthetic peptide that acts as a triple agonist at the glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon receptors
Obesity StatPearls
A., Stallknecht, B., Jensen, M
