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"GLP-1/GIP/glucagon receptor tri-agonism: the emerging paradigm in obesity pharmacotherapy." Endocrinology and Metabolism

In a subsequent prospective cohort, liraglutide not only improved metabolic parameters but also demonstrated immunomodulatory effects, with a significant reduction in circulating T-cell populations, particularly T cells, which are known to play a key role in PsO pathogenesis by producing IL17 and IL22 (26)

There have also been several reported conflicting results

GLP-1s facilitate weight loss by regulating appetite

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The clinical relevance of these findings is underscored by the safety profile of GLP-1 agonists in long-term use and their established efficacy in reducing cardiovascular events