retatrutide triple agonist glp-1 gip glucagon Dual and Gut Peptide Agonists on the Horizon for the Treatment of Type 2 Diabetes and Obesity. An Overview of Preclinical and Clinical Data Why Retatrutide is different ๐
Description
Liver enzymes (ALT, AST): Elevated liver enzymes before starting GLP-1 therapy common in people with non-alcoholic fatty liver disease, which frequently accompanies the metabolic conditions these medications treat need to be documented
This physiological response reduces caloric intake naturally without requiring conscious restriction

People Going Blind From GLP-1: Risks, Evidence and Protection Recent reports have raised concerns about potential links between GLP-1 medications and vision problems, prompting questions about whether people are going blind from GLP-1 treatments

Therefore, in patients where the fasting glucose is a more dominant feature of their hyperglycemia, metformin may be more appropriate, while GLP-1RAs could be better suited for those with postprandial hyperglycemia

Other important contributing factors are eating disorders and depression, which are more common in patients with T1D compared to the overall population (18, 19)
Dulaglutide Eli Lillys Trulicity is the only available version of dulaglutide
