is trulicity a glp-1 receptor agonists Semaglutide vs. Other GLP1 receptor agonist @nejm revisión

Since the mean/median duration for each of these studies was 100,000 patients prescribed a GLP-1RA, after propensity matching, there was reduced risk for PDAC during a 5-year observation period for GLP-1RA users compared to six categories of commonly used diabetes medication classes 44

The "Fuss" About GLP-1 Receptor Agonists The excitement surrounding GLP-1 receptor agonists stems from their effectiveness in not just managing blood sugar but also offering additional health benefits like weight loss and cardiovascular protection

What are the drawbacks of GLP-1s

T2DM: type 2 diabetes mellitus

Subcutaneous liraglutide ameliorates methylglyoxal-induced Alzheimer-like tau pathology and cognitive impairment by modulating tau hyperphosphorylation and glycogen synthase kinase-3beta

In addition, many of these patients will have additional risk factors for delayed gastric emptying (for example, diabetes or obesity) which must be taken into consideration