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Supplements such as BCAA (512 g/day), leucine (6 g/day), -Hydroxy--methylbutyrate (3 g/day), creatine (20 g/day for 57 days, followed by maintenance dose of 35 g/day), omega-3 fatty acids (24 g/day) and vitamin D (8001000 IU/day) may offer additional benefits in improving the health and quality of life of patients with sarcopenia, especially when balanced hypocaloric diet with adequate protein intake and physical exercise are insufficient to maintain muscle mass and function [50]

The multiple hit hypothesis has emerged as the dominant theory in recent years, indicating the collective impact of immunological mechanisms in the liver, intestines, and adipose tissue on the progression of MASLD [13]

Insulin & HbA1c: Determining the severity of insulin resistance helps us dose correctly

Red Flags: Declining kidney function may require medication adjustments or increased hydration

Adjusting the dosage under medical supervision is recommended

LLMs similarly destabilise assumptions about uniquely human cognition