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Gary Clayman, MD, explained that while animal studies have suggested a link between GLP-1 therapies and C-cell issues leading to medullary thyroid cancer, these findings have not been replicated in human studies

But for some, the drugs come with side effects they say aren't worth it.

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The increase in insulin secretion is mediated by a GABA-dependent relay in the paraventricular hypothalamus and decreased sympathetic nerve activity.

Independent editorial review of Noom
