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This can include medications like Metformin, Naltrexone, or Bupropion, and in some cases, they do offer access to GLP-1 agonists

However, in people with obesity, the brains response to dopamine can become blunted, meaning that they may not feel as satisfied or rewarded after eating

Participants receiving semaglutide lost an average of 12-15% of their starting body weight over 68 weeks, compared to 2-3% in the placebo group

Gallbladder problems , such as cholelithiasis or cholecystitis, occur more frequently with semaglutide, particularly during rapid weight loss, so patients with a history of gallbladder disease need monitoring

Vitamin B12 is important for brain and mental health, bone health, energy, heart health, and reduced risk of anemia

Fortunately, these effects can be managed with the right approach