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average age of the cohort: 17.7 3.4 years) nave to human Ig were initially screened by a physical examination, metabolic and safety clinical chemistry profiling, hematology, DXA (using a GE Lunar iDXA scanner) for body composition, and a liver biopsy for nonalcoholic fatty liver disease plus fibrosis (NAS + ) scoring

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A summary of the interactions of GLP-1 with the brainstem, hypothalamus and higher brain centres is shown in Fig

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