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A GIP receptor agonist enhanced Bcl-2 levels and reduced BAX levels in the MPTP mouse model of PD [154, 155]

24, 2025, in JAMA Internal Medicine followed 308 people taking tirzepatide for 36 weeks

Availability of Data and Material Not applicable Ethics Approval Not applicable Consent to Participate Not applicable Consent for Publication Not applicable Author Contributions All authors (F.P, S.M.O, J.M, F.C.S) meet ICMJE authorship criteria, made substantial contributions to the conception and design of the work and to drafting or critically revising the manuscript, approved the final version, and agree to be accountable for all aspects of the work

Diabetes Obes Metab 2023;25:138597

Sequential approach most practical for many patients: Start tirzepatide now

It may cause you to skip meals, which can trigger your metabolism to significantly slow down
