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As TGR5-mediated BA signaling also plays a role in the regulation of GLP-1 production, we analyzed the percentage of TGR5-agonistic BAs in the ileum of MMI mice before and after T3 treatment

Blood pressure improvements appear with both medications, typically in the range of 5 to 10 mmHg systolic reduction

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This effect is coupled with a downregulation of dopaminergic tone in mesolimbic structures, including the VTA and NAc, leading to reduced reward sensitivity [13,31]

Parkinson's disease, insulin resistance and novel agents of neuroprotection
