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Among the mechanisms, our research group and others have demonstrated that the gut microbiota fermentation (i.e., bacterial digestion of specific compounds) of specific prebiotics or other non-digestible carbohydrates is associated with the secretion of enteroendocrine peptides, such as the glucagon-like peptide-1 (GLP-1) and peptide YY (PYY), produced by L-cells

Probiotics may be compatible with semaglutide, but timing, strain selection, and individual GI responses matter significantly

In user experience studies, up to 96.65% of participants reported a significant reduction in joint pain within just two weeks, along with improved mobility and daily comfort