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Because the prevalence of CVD in the population with T2DM is around 32% [33], at least one fourth of the average patient with T2DM is possible a candidate for the use of the GLP-1RA, or sodium-glucose transporter-2 inhibitors [34], to improve the MACE outcome

As mentioned above, inflammatory responses and immunity are involved in the development and onset of depression ( Figure 2 )

Some may contain ingredients that have only been studied in small or preliminary trials, while others rely on marketing claims rather than strong clinical research
Therefore, current treatment guidelines recommend maintenance of an optimal weight and stringent management of lipid levels in addition to glycemic control [3]

GLP-1 drugs might also promote weight loss by reducing the amount of visceral fat the type of fat that surrounds organs and can contribute to conditions like obesity , fatty liver disease, and diabetes

1AG), denoted only by a moderate reduction in HOMA-IR (Fig