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Record Weight Loss Extensive Research The SURMOUNT clinical trial program demonstrated unprecedented weight loss with tirzepatide, averaging 22.5% of body weight at the highest dose (15mg weekly) in the SURMOUNT-1 trial - weight loss comparable to bariatric surgery

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The PURE study (Lancet, 2015, ~140,000 people) found grip strength predicts mortality better than blood pressure

But those numbers undercount the reality, because many people do not report burping as a side effect

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Compounded tirzepatide is prepared in FDA-registered and inspected compounding pharmacies, though it is not FDA-approved like the branded versions