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Description
Early clinical trial data suggest impressive benefits, with reports of up to 24% body weight loss in under a year

A major role of the hormone is to regulate the glucose homeostasis in a glucose-dependent manner as a result of its insulinotropic and glucagonostatic actions

PMID: 41400575

The subject was not using any prescription or over-the-counter skincare or medications during the study period

The diet-induced obesity (DIO)-resistant phenotype of conventional GIPR KO mice could be partially restored by reintroducing GIPR in adipose tissue using the aP2 promoter [103], and adipocyte-specific GIPR KO (GIPR adipo/ ) mice exhibited a marginally greater resistance to DIO compared to their wild-type counterparts [104]

A 2023 meta-analysis in Obesity Journal found modest but consistent benefits: 34 kg average weight loss at 6 months in app-based interventions versus control groups
