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Early clinical trials focused primarily on glycaemic control and absolute weight reduction, often under-reporting subtle shifts in cycle health

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These factors should be considered when interpreting observed associations

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Foods to limit or approach cautiously: High-fat foods: Fried foods, fatty cuts of meat, full-fat dairy, and excessive oils may exacerbate nausea and provide excessive calories relative to satiety Ultra-processed foods: Biscuits, crisps, confectionery, and processed snacks are typically calorie-dense and nutrient-poor Sugary beverages: Soft drinks, fruit juices, and sweetened coffees provide calories without promoting fullness Large portion sizes: Even of healthy foods, as Wegovy's effect on gastric emptying means large meals may cause discomfort Alcohol: Provides empty calories and may impair judgement around food choices

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Understanding these possible factors can help address fatigue more effectively

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