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The study noted some significant findings

Patients should discontinue all motility-altering medications, including prokinetics, opiates and anticholinergics for at least 23 days before testing, and longer if possible

However, the full appetite-regulating effects become more noticeable after 2-4 weeks as the body adjusts to the medication

Your provider may adjust this schedule based on your health history and genetic test results from the Precision Peptide Genetic Test

Recent studies have found that increased level of GLP-1 in the hippocampus restores GABA and reverses this neurotoxic effect by reducing oxidative stress through the SIRT1/Nrf2/HO-1 pathway, promoting autophagy through the AMPK/mTOR pathway, and alleviating hippocampal apoptosis by inactivating pro-apoptotic kinase GSK-3 (Arab et al., 2023)
