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Research indicates that stopping or interrupting obesity treatments, particularly weight-loss medications like GLP-1 drugs, frequently results in a rapid regain of lost weight

Management: Use with caution under medical supervision and report any unusual symptoms

Patients with a naturally smaller optic disc (where the nerve connects to the eye) are already at higher risk for NAION, according to the American Optometric Association

Semaglutide, the active peptide in Wegovy/Ozempic, is a glucagon-like peptide 1 mimetic, or glucagon-like peptide 1 receptor agonist (GLP-1RA)

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But these health issues may raise your risk: Diabetes High blood pressure High cholesterol Obstructive sleep apnea Taking certain medications (PDE4 inhibitors) Smoking Eye problems that can increase your risk include: Previous NAION in one eye A naturally crowded optic nerve (called disk at risk) Having prior eye surgery You can still take semaglutide or other GLP-1 drugs if you have these conditions