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Whilst all GLP-1RAs use has increased, the largest change was seen in patients using tirzepatide and semaglutide ([figure 1B][1])

At present, GLP-1RAs have become highly effective treatments for managing type 2 diabetes mellitus and obesity

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A UCLA study published in ACR Open Rheumatology found that GLP-1 receptor agonists such as semaglutide and tirzepatide may reduce rheumatoid arthritis activity and cardiovascular risk factors in people with obesity, suggesting potential dual benefits for metabolic and inflammatory health.

(bkz: glp)