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The Liver in Regulation of Energy Metabolism: A Perspective on the Interplay Between Estrogen and the Liver (PMID: 26454069, PMC4600502) The liver is not only a nutrient-processing organ - it is also a central target and regulator for sex hormones such as estrogens

injections of 100 nmol kg 1 GLP-1MK-801 ( n = 8 mice and n = 4 cages), 300 nmol kg 1 GLP-1MK-801 ( n = 8 mice and n = 4 cages) or vehicle (isotonic saline, n = 8 mice and n = 4 cages) for 14 days

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When activated, these receptors trigger a cascade of effects including reduced appetite, slowed gastric emptying, and enhanced insulin sensitivity