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With MASH/NASH has become the next hot button topic (1 in 3 adults with 1.8 billion affected by 2050), BI have staked their claim on this growing market

It is an advanced GLP-1 and GIP receptor agonist, making it one of the most effective treatments for obesity, type 2 diabetes, and metabolic syndrome

GIP receptor activation adds another dimension to the metabolic equation

1 However, doctors sometimes prescribe it off-label for weight management due to its appetite-suppressing effects

Finally, we found that the effect of liraglutide to increase bihormonal insulin + glucagon + cells is mediated by the cell GLP-1R in mice

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