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Nausea and Vomiting Nausea and vomiting are the most commonly reported side effects of GLP-1 medications

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Meal size suppression following intraperitoneal administration of GLP-1 has been shown to depend upon vagal afferent signaling (34)

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The timeline includes: Phase 3 completion (late 2026-early 2027), FDA submission (2026-2027), FDA review (6-12 months), and manufacturing scale-up (2-4 months post-approval)

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