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Author Contributions SP and NK contributed equally to the work and were responsible for drafting and writing of the manuscript, searching of literature and interpreting of data

Top-dose phentermine and topiramate was not cost-effective, with an ICER of $317,010 per QALY gained vs lifestyle counselling

In fact, patients with a constellation of upper GI symptoms including chronic nausea, early satiety, bloating, and abdominal pain may be better considered as one group of gastric neuromuscular disorders (GNDs) irrespective of gastric emptying results

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338 participants is not enough to detect rare but serious adverse events

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