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Eur J Endocrinol 143: 717-725, 2000 Villanueva-Penacarillo ML, Alcantara AI, Clemente F, Delgado E, Valverde I

Consult a qualified healthcare professional before making changes to your diet, supplement routine, or treatment, especially if you are managing a health condition or taking medication

Glucagon AUC was significantly lower on day 5 with exenatide compared with placebo, P = .0123

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GLP-1 receptor agonists mimic the action of naturally occurring hormones that regulate blood glucose and appetite by: Slowing gastric emptying, promoting feelings of fullness Reducing appetite signals in the brains hunger centers Improving insulin secretion while suppressing glucagon release Creating a caloric deficit through reduced food intake Originally developed for type 2 diabetes management, these medications have gained FDA approval for chronic weight management in adults with obesity or overweight with weight-related comorbidities

No 2 weeks is too early to evaluate a new dose