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N Engl J Med 2008;358:25602572 [DOI] [PubMed] [Google Scholar] 8.Canadian Diabetes Association Clinical Practice Guidelines Expert Committee

Results last up to two years

This arm produced the largest average weight loss but also the highest rate of gastrointestinal side effects

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J Clin Endocrinol Metab 2017

(2) number of included trials (highest if 24 months apart)
