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Tirzepatide targets both the GLP-1 and GIP receptors simultaneously, creating what researchers call a "twincretin" effect

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Nisha Patel, medical director of the Obesity Medicine and Metabolic Health Program within the transplant department at California Pacific Medical Center in San Francisco

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Taking doses other than what is prescribed by your provider may have unintended and potentially dangerous side effects

If additional weight loss is needed and the medication is well-tolerated, your healthcare provider may increase the dose in 2.5 mg increments, no more frequently than every 4 weeks