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Both groups took the 2.5 mg tablet once daily for 28 days
The relationship between these neurochemical markers and the kynurenine pathway underscores a promising avenue for future research, emphasizing how these biological indicators can enhance clinical practices
These preclinical findings support clinical trial results showing that tirzepatide, a dual GIPR/GLP-1R agonist, exhibits greater anti-obesity effects than GLP-1 receptor agonists alone
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Finally, if broad GLP-1 coverage is not feasible, prioritizing coverage for individuals with high severity (BMI over 40) or those with comorbidities and risk factors can be a practical starting point
Broad cardiometabolic risk factor modification
