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Am J Psychiatry 180(8):565572 Leggio L, Hendershot CS, Farokhnia M, Fink-Jensen A, Klausen MK, Schacht JP, Simmons WK (2023) GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use disorders

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11,227,228 Islet alpha-cell GLP-1R knockout mice were unable to inhibit glucagon secretion at high glucose levels, and surprisingly, these mice exhibited reduced glucagon secretion during low glucose conditions

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