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However, important questions remain about their precise mechanisms of action, potential adverse effects, and which patient subgroups are most likely to benefit

This impending patent cliff is a material headwind for Novo Nordisk, but price reductions will drive a substantial uplift in the volume of patients on injectable semaglutide, through preferential reimbursement (by state or PMI payors) and improved affordability for the self-pay segment

10.1038/aps.2016.21 140 ZubiagaL.BriandO.AugerF.ToucheV.HubertT.ThevenetJ.et al (2023)

In addition, the NTS houses numerous neuropeptides that are capable of modulating HPA axis stress responses, including glucagon-like peptide-1 (GLP-1), somatostatin, substance P, neuropeptide Y and enkephalin [15, 18, 35]

10.1016/j.it.2008.02.010 6

The science behind the link Well, RA isnt just joint pain its an autoimmune disease linked with inflammation, metabolic issues (obesity, insulin resistance), and cardiovascular risk
