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With the successive launch of Glucagon-like peptide-1 (GLP-1) class drugs that allow weight loss with a once-daily pill instead of an injection, the barrier to obesity treatment is lowering

Evidence from experimental and clinical studies indicates that various diets, including Mediterranean, Nordic, Palaeolithic and ketogenic diets, increase insulin sensitivity, decrease gluconeogenesis, and adiposity, and exert anti-inflammatory effects, thus preserving immuno-metabolic homeostasis in individuals with T2D

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Heart failure patients could be the next group to benefit from GLP-1 agonists, which are currently approved for the treatment of diabetes and obesity.

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