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Common side effects include nausea, vomiting, diarrhoea, and a modest increase in resting heart rate linked to glucagon receptor agonism

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Some additional health conditions that can contribute to weight gain and cause difficulty losing weight include: Polycystic ovary syndrome (PCOS) Heart failure Kidney or liver problems Metabolic conditions like high blood pressure and cholesterol Thyroid disease (especially hypothyroidism) If you have other health conditions, talk to your healthcare provider about whether they could be affecting your weight loss on semaglutide

It can cause depression