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In parallel, multi-target agents offer synergistic metabolic and weight-lowering effects, as exemplified by retatrutide (GLP-1R/GIPR/GCGR agonist) and NA931 (GLP-1R/GIPR/GCGR/IGF1 agonist), both of which demonstrate potent efficacy with acceptable tolerability (Rosenstock et al., 2023

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Practical strategies for managing treats include: Portion control : Use small bowls or purchase individual serving sizes rather than large tubs Frequency planning : Designate specific occasions for treats rather than keeping them readily available Nutritional awareness : Read labels to understand calorie and sugar content per serving Lower-calorie alternatives : Consider frozen yoghurt, sorbet, or reduced-fat ice cream options Mindful eating : Eat slowly, without distractions, to fully enjoy smaller portions Some patients find that planning treats in advance helps maintain control whilst still allowing enjoyment

(In Spanish) [DOI] [PubMed] [Google Scholar] 20.American Society of Anesthesiologists Consensus-Based Guidance on Preoperative Management of Patients (Adults and Children) on Glucagon-like Peptide-1 (GLP-1) Receptor Agonists