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307,413 In terms of apoptosis inhibition, GLP-1 activates the PI3K/Akt signaling pathway, enhances the expression of the anti-apoptotic protein Bcl-2, and inhibits the activation of caspase family proteins, reducing cell apoptosis

Plan selection during the next Annual Enrollment Period will be critical if you want continued GLP-1 access

Retrieved March 10, 2026, from 2 VCUHealth

Carlessi, R., Chen, Y., Rowlands, J., Cruzat, V