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In combination with glimepiride, with or without metformin, the overall incidence of clinical adverse reactions with sitagliptin was higher than with placebo, in part related to a higher incidence of hypoglycemia (see Table 3)

The most common side effects reported in clinical trials are gastrointestinal, including nausea, vomiting, and constipation

Accuracy matters

"As a medical community we are obtaining a better understanding of the physiology and hormones that create and maintain weight gain and this is allowing for improved treatment options of a complex medical condition