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The monotherapy group had a difference in HbA1c % from baseline of 0.14% vs -0.9% in the combination group (p=0.007)
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At six months, patients treated with tirzepatide experienced greater average weight loss (-11.15% vs -8.83%)

The findings revealed a crucial insight, for some GLP-1 s like Saxenda and Wegovy, the high cost of ongoing use surpasses the cost of RYGB in less than a year and sleeve gastrectomy within nine months

Truveta Research finds tirzepatide more effective than semaglutide for weight loss in patients with overweight or obesity.
